Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases

The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 p...

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Autores principales: KOUSI, EVANTHIA, TSOUGOS, IOANNIS, FOUNTAS, KONSTANTINOS, THEODOROU, KIRIAKI, TSOLAKI, EVAGGELIA, FEZOULIDIS, IOANNIS, KAPSALAKI, EFTICHIA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493044/
https://www.ncbi.nlm.nih.gov/pubmed/22293950
http://dx.doi.org/10.3892/mmr.2012.773
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author KOUSI, EVANTHIA
TSOUGOS, IOANNIS
FOUNTAS, KONSTANTINOS
THEODOROU, KIRIAKI
TSOLAKI, EVAGGELIA
FEZOULIDIS, IOANNIS
KAPSALAKI, EFTICHIA
author_facet KOUSI, EVANTHIA
TSOUGOS, IOANNIS
FOUNTAS, KONSTANTINOS
THEODOROU, KIRIAKI
TSOLAKI, EVAGGELIA
FEZOULIDIS, IOANNIS
KAPSALAKI, EFTICHIA
author_sort KOUSI, EVANTHIA
collection PubMed
description The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was not indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy.
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spelling pubmed-34930442013-04-01 Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases KOUSI, EVANTHIA TSOUGOS, IOANNIS FOUNTAS, KONSTANTINOS THEODOROU, KIRIAKI TSOLAKI, EVAGGELIA FEZOULIDIS, IOANNIS KAPSALAKI, EFTICHIA Mol Med Rep Article The purpose of the present study was to evaluate distinct metabolic features of meningiomas to distinguish them from other brain lesions using proton magnetic resonance spectroscopy. The study was performed on 17 meningiomas, 24 high-grade gliomas and 9 metastases. Elevated signal intensity at 3.8 ppm observed in low TE spectra adequately differentiated meningioma from other brain tumors while alanine was not indicative of meningioma occurrence; the presence of lipids and lactate did not provide a strong index for meningioma malignancy. D.A. Spandidos 2012-01-30 2012-04 /pmc/articles/PMC3493044/ /pubmed/22293950 http://dx.doi.org/10.3892/mmr.2012.773 Text en Copyright © 2012, Spandidos Publications
spellingShingle Article
KOUSI, EVANTHIA
TSOUGOS, IOANNIS
FOUNTAS, KONSTANTINOS
THEODOROU, KIRIAKI
TSOLAKI, EVAGGELIA
FEZOULIDIS, IOANNIS
KAPSALAKI, EFTICHIA
Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
title Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
title_full Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
title_fullStr Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
title_full_unstemmed Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
title_short Distinct peak at 3.8 ppm observed by 3T MR spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
title_sort distinct peak at 3.8 ppm observed by 3t mr spectroscopy in meningiomas, while nearly absent in high-grade gliomas and cerebral metastases
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493044/
https://www.ncbi.nlm.nih.gov/pubmed/22293950
http://dx.doi.org/10.3892/mmr.2012.773
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