Cargando…
Pitfalls in the detection of cholesterol in Huntington’s disease models
Background Abnormalities in brain cholesterol homeostasis have been reported in Huntington’s disease (HD), an adult-onset neurodegenerative disorder caused by an expansion in the number of CAG repeats in the huntingtin (HTT) gene. However, the results have been contradictory with respect to whether...
Autores principales: | Marullo, Manuela, Valenza, Marta, Leoni, Valerio, Caccia, Claudio, Scarlatti, Chiara, De Mario, Agnese, Zuccato, Chiara, Di Donato, Stefano, Carafoli, Ernesto, Cattaneo, Elena |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493072/ https://www.ncbi.nlm.nih.gov/pubmed/23145355 http://dx.doi.org/10.1371/505886e9a1968 |
Ejemplares similares
-
High-Throughput Automated Phenotyping of Two Genetic Mouse Models of Huntington's Disease
por: Balci, Fuat, et al.
Publicado: (2013) -
Dysfunctional mitochondrial respiration in the striatum of the Huntington’s disease transgenic R6/2 mouse model
por: Aidt, Frederik Heurlin, et al.
Publicado: (2013) -
Characterization of Striatal Neuronal Loss and Atrophy in the R6/2 Mouse Model of Huntington’s Disease
por: Dodds, Lindsay, et al.
Publicado: (2014) -
Deficits in a Simple Visual Go/No-go Discrimination Task in Two Mouse Models of Huntington’s Disease
por: Oakeshott, Stephen, et al.
Publicado: (2013) -
Caspase-6 does not contribute to the proteolysis of mutant huntingtin in the HdhQ150 knock-in mouse model of Huntington’s disease
por: Landles, Christian, et al.
Publicado: (2012)