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Selective detection of bacterial layers with terahertz plasmonic antennas
Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infec...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Optical Society of America
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493226/ https://www.ncbi.nlm.nih.gov/pubmed/23162730 http://dx.doi.org/10.1364/BOE.3.002937 |
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author | Berrier, Audrey Schaafsma, Martijn C. Nonglaton, Guillaume Bergquist, Jonas Rivas, Jaime Gómez |
author_facet | Berrier, Audrey Schaafsma, Martijn C. Nonglaton, Guillaume Bergquist, Jonas Rivas, Jaime Gómez |
author_sort | Berrier, Audrey |
collection | PubMed |
description | Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria. |
format | Online Article Text |
id | pubmed-3493226 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Optical Society of America |
record_format | MEDLINE/PubMed |
spelling | pubmed-34932262012-11-16 Selective detection of bacterial layers with terahertz plasmonic antennas Berrier, Audrey Schaafsma, Martijn C. Nonglaton, Guillaume Bergquist, Jonas Rivas, Jaime Gómez Biomed Opt Express Spectroscopic Diagnostics Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria. Optical Society of America 2012-10-23 /pmc/articles/PMC3493226/ /pubmed/23162730 http://dx.doi.org/10.1364/BOE.3.002937 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially. |
spellingShingle | Spectroscopic Diagnostics Berrier, Audrey Schaafsma, Martijn C. Nonglaton, Guillaume Bergquist, Jonas Rivas, Jaime Gómez Selective detection of bacterial layers with terahertz plasmonic antennas |
title | Selective detection of bacterial layers with terahertz plasmonic antennas |
title_full | Selective detection of bacterial layers with terahertz plasmonic antennas |
title_fullStr | Selective detection of bacterial layers with terahertz plasmonic antennas |
title_full_unstemmed | Selective detection of bacterial layers with terahertz plasmonic antennas |
title_short | Selective detection of bacterial layers with terahertz plasmonic antennas |
title_sort | selective detection of bacterial layers with terahertz plasmonic antennas |
topic | Spectroscopic Diagnostics |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493226/ https://www.ncbi.nlm.nih.gov/pubmed/23162730 http://dx.doi.org/10.1364/BOE.3.002937 |
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