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Selective detection of bacterial layers with terahertz plasmonic antennas

Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infec...

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Autores principales: Berrier, Audrey, Schaafsma, Martijn C., Nonglaton, Guillaume, Bergquist, Jonas, Rivas, Jaime Gómez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Optical Society of America 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493226/
https://www.ncbi.nlm.nih.gov/pubmed/23162730
http://dx.doi.org/10.1364/BOE.3.002937
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author Berrier, Audrey
Schaafsma, Martijn C.
Nonglaton, Guillaume
Bergquist, Jonas
Rivas, Jaime Gómez
author_facet Berrier, Audrey
Schaafsma, Martijn C.
Nonglaton, Guillaume
Bergquist, Jonas
Rivas, Jaime Gómez
author_sort Berrier, Audrey
collection PubMed
description Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria.
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spelling pubmed-34932262012-11-16 Selective detection of bacterial layers with terahertz plasmonic antennas Berrier, Audrey Schaafsma, Martijn C. Nonglaton, Guillaume Bergquist, Jonas Rivas, Jaime Gómez Biomed Opt Express Spectroscopic Diagnostics Current detection and identification of micro-organisms is based on either rather unspecific rapid microscopy or on more accurate but complex and time-consuming procedures. In a medical context, the determination of the bacteria Gram type is of significant interest. The diagnostic of microbial infection often requires the identification of the microbiological agent responsible for the infection, or at least the identification of its family (Gram type), in a matter of minutes. In this work, we propose to use terahertz frequency range antennas for the enhanced selective detection of bacteria types. Several microorganisms are investigated by terahertz time-domain spectroscopy: a fast, contactless and damage-free investigation method to gain information on the presence and the nature of the microorganisms. We demonstrate that plasmonic antennas enhance the detection sensitivity for bacterial layers and allow the selective recognition of the Gram type of the bacteria. Optical Society of America 2012-10-23 /pmc/articles/PMC3493226/ /pubmed/23162730 http://dx.doi.org/10.1364/BOE.3.002937 Text en ©2012 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Spectroscopic Diagnostics
Berrier, Audrey
Schaafsma, Martijn C.
Nonglaton, Guillaume
Bergquist, Jonas
Rivas, Jaime Gómez
Selective detection of bacterial layers with terahertz plasmonic antennas
title Selective detection of bacterial layers with terahertz plasmonic antennas
title_full Selective detection of bacterial layers with terahertz plasmonic antennas
title_fullStr Selective detection of bacterial layers with terahertz plasmonic antennas
title_full_unstemmed Selective detection of bacterial layers with terahertz plasmonic antennas
title_short Selective detection of bacterial layers with terahertz plasmonic antennas
title_sort selective detection of bacterial layers with terahertz plasmonic antennas
topic Spectroscopic Diagnostics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493226/
https://www.ncbi.nlm.nih.gov/pubmed/23162730
http://dx.doi.org/10.1364/BOE.3.002937
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