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RNA polymerase I-driven reverse genetics system for enterovirus 71 and its implications for vaccine production
BACKGROUND: Enterovirus 71 (EV71) is a virus that causes from mild hand, foot and mouth disease (HFMD) to severe neurological complications and deaths in infants and young children. Effective antiviral agents and vaccines against EV71 are not available. However, Vero cell-based chemically inactivate...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493273/ https://www.ncbi.nlm.nih.gov/pubmed/23072515 http://dx.doi.org/10.1186/1743-422X-9-238 |