Cargando…

Naturally occurring mutations to HCV protease inhibitors in treatment-naïve patients

BACKGROUND: Protease inhibitors (PIs) to treat hepatitis C (HCV) virus infection have been approved and others are under development. RESULTS: The aims of this study were to illustrate natural polymorphisms in the HCV protease and measure the frequency of PI resistance mutations in different HCV gen...

Descripción completa

Detalles Bibliográficos
Autores principales:	Paolucci, Stefania, Fiorina, Loretta, Piralla, Antonio, Gulminetti, Roberto, Novati, Stefano, Barbarini, Giorgio, Sacchi, Paolo, Gatti, Marta, Dossena, Luca, Baldanti, Fausto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493344/ https://www.ncbi.nlm.nih.gov/pubmed/23095680 http://dx.doi.org/10.1186/1743-422X-9-245

Ejemplares similares

Naturally occurring resistance mutations to inhibitors of HCV NS5A region and NS5B polymerase in DAA treatment-naïve patients
por: Paolucci, Stefania, et al.
Publicado: (2013)

Viral dynamics among HCV infected patients with different genotypes treated with genotypic specific or pan-genotypic direct-acting antiviral agent combinations
por: Paolucci, Stefania, et al.
Publicado: (2019)

Baseline and Breakthrough Resistance Mutations in HCV Patients Failing DAAs
por: Paolucci, Stefania, et al.
Publicado: (2017)

Baseline Amino Acid Substitutions in the NS5A ISDR and PKR Binding Domain of Hepatitis C and Different Fibrosis Levels and Levels of Development of Hepatocellular Carcinoma in Patients Treated with DAAs
por: Paolucci, Stefania, et al.
Publicado: (2020)

HIV integrase variability and genetic barrier in antiretroviral naïve and experienced patients
por: Piralla, Antonio, et al.
Publicado: (2011)

EBV DNA increase in COVID-19 patients with impaired lymphocyte subpopulation count
por: Paolucci, Stefania, et al.
Publicado: (2021)

SARS‐CoV‐2 infections in pediatric patients: A comparison of three pandemic waves
por: Rovida, Francesca, et al.
Publicado: (2022)

Case report: Successful outcome of COVID-19 in the context of autologous hematopoietic stem cell transplantation: The impact of the anti-SARS-CoV-2 vaccine and early remdesivir
por: Lasagna, Angioletta, et al.
Publicado: (2022)

Evaluation of the Neutralizing Antibodies Response against 14 SARS-CoV-2 Variants in BNT162b2 Vaccinated Naïve and COVID-19 Positive Healthcare Workers from a Northern Italian Hospital
por: Sammartino, Josè Camilla, et al.
Publicado: (2022)

Genetic divergence of influenza A NS1 gene in pandemic 2009 H1N1 isolates with respect to H1N1 and H3N2 isolates from previous seasonal epidemics
por: Campanini, Giulia, et al.
Publicado: (2010)

Correlations between atazanavir C(trough )and hyperbilirubinemia: a case report
por: Uglietti, Alessia, et al.
Publicado: (2009)

Spread of multiple SARS‐CoV‐2 lineages April‐August 2020 anticipated the second pandemic wave in Lombardy (Italy)
por: Tallarita, Monica, et al.
Publicado: (2022)

No evidence of SARS-CoV-2 circulation in the framework of influenza surveillance between October 2019 and February 2020 in Lombardy, Italy
por: Giardina, Federica, et al.
Publicado: (2021)

Systematic analysis of human oncogenic viruses in colon cancer revealed EBV latency in lymphoid infiltrates
por: Fiorina, Loretta, et al.
Publicado: (2014)

Naturally occurring mutations associated with resistance to HCV NS5B polymerase and NS3 protease inhibitors in treatment-naïve patients with chronic hepatitis C
por: Costantino, Angela, et al.
Publicado: (2015)

Natural Polymorphisms Conferring Resistance to HCV Protease and Polymerase Inhibitors in Treatment-Naïve HIV/HCV Co-Infected Patients in China
por: Zhou, Kali, et al.
Publicado: (2016)

Clinical characteristics of coronavirus disease (COVID-19) early findings from a teaching hospital in Pavia, North Italy, 21 to 28 February 2020
por: Colaneri, Marta, et al.
Publicado: (2020)

Enterovirus Genotype EV-104 in Humans, Italy, 2008–2009
por: Piralla, Antonio, et al.
Publicado: (2010)

Frequency of respiratory viruses among patients admitted to 26 Intensive Care Units in seven consecutive winter-spring seasons (2009–2016) in Northern Italy
por: Piralla, Antonio, et al.
Publicado: (2017)

Cellular DNA quantification in respiratory samples for the normalization of viral load: a real need?
por: Piralla, Antonio, et al.
Publicado: (2018)

Comparative analysis of SARS-CoV-2 quasispecies in the upper and lower respiratory tract shows an ongoing evolution in the spike cleavage site
por: Gaiarsa, Stefano, et al.
Publicado: (2022)

Pre-existing resistance associated polymorphisms to NS3 protease inhibitors in treatment naïve HCV positive Pakistani patients
por: Khan, Hafeez Ullah, et al.
Publicado: (2020)

Antibody therapy for COVID-19
por: Hammarström, Lennart, et al.
Publicado: (2021)

Severe acute respiratory syndrome coronavirus 2 RNA contamination of inanimate surfaces and virus viability in a health care emergency unit
por: Colaneri, M., et al.
Publicado: (2020)

Naturally Occurring Mutations in the Nonstructural Region 5B of Hepatitis C Virus (HCV) from Treatment-Naïve Korean Patients Chronically Infected with HCV Genotype 1b
por: Kim, Dong-Won, et al.
Publicado: (2014)

Naturally Occurring Resistance Associated Substitutions in Non-Cirrhotic, Treatment Naive HCV–HIV Co-Infected Patients Does Not Affect the Treatment Response for Anti-HCV Antiviral Therapy
por: Gupta, Ekta, et al.
Publicado: (2021)

Hierarchical Naive Bayes for genetic association studies
por: Malovini, Alberto, et al.
Publicado: (2012)

Mycobacterium chimaera Identification Using MALDI-TOF MS Technology: A Practical Approach for the Clinical Microbiology Laboratories
por: Bagnarino, Jessica, et al.
Publicado: (2022)

Emerging and re-emerging virus infections in neonates and young pediatric patients
por: Baldanti, Fausto, et al.
Publicado: (2014)

Persistent rhinovirus infection in pediatric hematopoietic stem cell transplant recipients with impaired cellular immunity
por: Piralla, Antonio, et al.
Publicado: (2015)

Looking for fever in nursing home residents with COVID-19: A false friend?
por: Raimondi, Ambra, et al.
Publicado: (2021)

Swine Influenza A(H3N2) Virus Infection in Immunocompromised Man, Italy, 2014
por: Piralla, Antonio, et al.
Publicado: (2015)

The novel influenza A virus protein PA-X and its naturally deleted variant show different enzymatic properties in comparison to the viral endonuclease PA
por: Bavagnoli, Laura, et al.
Publicado: (2015)

SARS-CoV-2 positivity in rectal swabs: implication for possible transmission
por: Novazzi, Federica, et al.
Publicado: (2020)

Prevalence and epidemiological correlates and treatment outcome of HCV infection in an Italian prison setting
por: Brandolini, Micaela, et al.
Publicado: (2013)

Assessing the Efficacy of Early Therapies against SARS-CoV-2 in Hematological Patients: A Real-Life Study from a COVID-19 Referral Centre in Northern Italy
por: Colaneri, Marta, et al.
Publicado: (2022)

Full Genome Sequence of a Novel Human Enterovirus C (EV-C118) Isolated from Two Children with Acute Otitis Media and Community-Acquired Pneumonia in Israel
por: Daleno, Cristina, et al.
Publicado: (2013)

Persistent Human Cosavirus Infection in Lung Transplant Recipient, Italy
por: Campanini, Giulia, et al.
Publicado: (2013)

Letter to the editor: Need for a European network for enterovirus D68 surveillance after detections of EV-D68 of the new B3 lineage in Sweden and Italy, 2016
por: Pariani, Elena, et al.
Publicado: (2017)

Contribution of Enteroviruses to Acute Central Nervous System or Systemic Infections in Northern Italy (2015-2017): Is It Time to Establish a National Laboratory-Based Surveillance System?
por: Piralla, Antonio, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_fnh20hep04i732htvdhpe71ufj