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Transcription Factor Oct1 Is a Somatic and Cancer Stem Cell Determinant

Defining master transcription factors governing somatic and cancer stem cell identity is an important goal. Here we show that the Oct4 paralog Oct1, a transcription factor implicated in stress responses, metabolic control, and poised transcription states, regulates normal and pathologic stem cell fu...

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Detalles Bibliográficos
Autores principales: Maddox, Jessica, Shakya, Arvind, South, Samuel, Shelton, Dawne, Andersen, Jared N., Chidester, Stephanie, Kang, Jinsuk, Gligorich, Keith M., Jones, David A., Spangrude, Gerald J., Welm, Bryan E., Tantin, Dean
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493455/
https://www.ncbi.nlm.nih.gov/pubmed/23144633
http://dx.doi.org/10.1371/journal.pgen.1003048