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Transcription Factor Oct1 Is a Somatic and Cancer Stem Cell Determinant
Defining master transcription factors governing somatic and cancer stem cell identity is an important goal. Here we show that the Oct4 paralog Oct1, a transcription factor implicated in stress responses, metabolic control, and poised transcription states, regulates normal and pathologic stem cell fu...
Autores principales: | Maddox, Jessica, Shakya, Arvind, South, Samuel, Shelton, Dawne, Andersen, Jared N., Chidester, Stephanie, Kang, Jinsuk, Gligorich, Keith M., Jones, David A., Spangrude, Gerald J., Welm, Bryan E., Tantin, Dean |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493455/ https://www.ncbi.nlm.nih.gov/pubmed/23144633 http://dx.doi.org/10.1371/journal.pgen.1003048 |
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