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A Graphical Modelling Approach to the Dissection of Highly Correlated Transcription Factor Binding Site Profiles

Inferring the combinatorial regulatory code of transcription factors (TFs) from genome-wide TF binding profiles is challenging. A major reason is that TF binding profiles significantly overlap and are therefore highly correlated. Clustered occurrence of multiple TFs at genomic sites may arise from c...

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Detalles Bibliográficos
Autores principales:	Stojnic, Robert, Fu, Audrey Qiuyan, Adryan, Boris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493460/ https://www.ncbi.nlm.nih.gov/pubmed/23144600 http://dx.doi.org/10.1371/journal.pcbi.1002725

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