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Distinct Effects on Diversifying Selection by Two Mechanisms of Immunity against Streptococcus pneumoniae
Antigenic variation to evade host immunity has long been assumed to be a driving force of diversifying selection in pathogens. Colonization by Streptococcus pneumoniae, which is central to the organism's transmission and therefore evolution, is limited by two arms of the immune system: antibody...
Autores principales: | Li, Yuan, Gierahn, Todd, Thompson, Claudette M., Trzciński, Krzysztof, Ford, Christopher B., Croucher, Nicholas, Gouveia, Paulo, Flechtner, Jessica B., Malley, Richard, Lipsitch, Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493470/ https://www.ncbi.nlm.nih.gov/pubmed/23144610 http://dx.doi.org/10.1371/journal.ppat.1002989 |
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