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Enhancing Blockade of Plasmodium falciparum Erythrocyte Invasion: Assessing Combinations of Antibodies against PfRH5 and Other Merozoite Antigens
No vaccine has yet proven effective against the blood-stages of Plasmodium falciparum, which cause the symptoms and severe manifestations of malaria. We recently found that PfRH5, a P. falciparum-specific protein expressed in merozoites, is efficiently targeted by broadly-neutralizing, vaccine-induc...
Autores principales: | Williams, Andrew R., Douglas, Alexander D., Miura, Kazutoyo, Illingworth, Joseph J., Choudhary, Prateek, Murungi, Linda M., Furze, Julie M., Diouf, Ababacar, Miotto, Olivo, Crosnier, Cécile, Wright, Gavin J., Kwiatkowski, Dominic P., Fairhurst, Rick M., Long, Carole A., Draper, Simon J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493472/ https://www.ncbi.nlm.nih.gov/pubmed/23144611 http://dx.doi.org/10.1371/journal.ppat.1002991 |
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