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Human ALKBH4 Interacts with Proteins Associated with Transcription

The Fe(II)- and 2-oxoglutarate (2OG)-dependent dioxygenase AlkB from E. coli is a demethylase which repairs alkyl lesions in DNA, as well as RNA, through a direct reversal mechanism. Humans possess nine AlkB homologs (ALKBH1-8 and FTO). ALKBH2 and ALKBH3 display demethylase activities corresponding...

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Detalles Bibliográficos
Autores principales:	Bjørnstad, Linn G., Meza, Trine J., Otterlei, Marit, Olafsrud, Solveig M., Meza-Zepeda, Leonardo A., Falnes, Pål Ø.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493508/ https://www.ncbi.nlm.nih.gov/pubmed/23145062 http://dx.doi.org/10.1371/journal.pone.0049045

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