Cargando…
Loss of Imprinting and Allelic Switching at the DLK1-MEG3 Locus in Human Hepatocellular Carcinoma
Deregulation of imprinted genes is an important molecular mechanism contributing to the development of cancer in humans. However, knowledge about imprinting defects in human hepatocellular carcinoma (HCC), the third leading cause of cancer mortality worldwide, is still limited. Therefore, a systemat...
Autores principales: | Anwar, Sumadi Lukman, Krech, Till, Hasemeier, Britta, Schipper, Elisa, Schweitzer, Nora, Vogel, Arndt, Kreipe, Hans, Lehmann, Ulrich |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493531/ https://www.ncbi.nlm.nih.gov/pubmed/23145177 http://dx.doi.org/10.1371/journal.pone.0049462 |
Ejemplares similares
-
Loss of DNA methylation at imprinted loci is a frequent event in hepatocellular carcinoma and identifies patients with shortened survival
por: Anwar, Sumadi Lukman, et al.
Publicado: (2015) -
hsa-mir-183 is frequently methylated and related to poor survival in human hepatocellular carcinoma
por: Anwar, Sumadi Lukman, et al.
Publicado: (2017) -
LINE-1 hypomethylation in human hepatocellular carcinomas correlates with shorter overall survival and CIMP phenotype
por: Anwar, Sumadi Lukman, et al.
Publicado: (2019) -
Quantitative cross-validation and content analysis of the 450k DNA methylation array from Illumina, Inc.
por: Roessler, Jessica, et al.
Publicado: (2012) -
Regulation of the imprinted Dlk1-Dio3 locus by allele-specific enhancer activity
por: Luo, Zhuojuan, et al.
Publicado: (2016)