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Prime-Boost Vaccination with SA-4-1BBL Costimulatory Molecule and Survivin Eradicates Lung Carcinoma in CD8(+) T and NK Cell Dependent Manner

Subunit vaccines containing universal tumor associated antigens (TAAs) present an attractive treatment modality for cancer primarily due to their safety and potential to generate long-term immunological responses that can safeguard against recurrences. However, TAA-based subunit vaccines require pot...

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Detalles Bibliográficos
Autores principales: Srivastava, Abhishek K., Sharma, Rajesh K., Yolcu, Esma S., Ulker, Vahap, MacLeod, Kathryn, Dinc, Gunes, Shirwan, Haval
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493554/
https://www.ncbi.nlm.nih.gov/pubmed/23144888
http://dx.doi.org/10.1371/journal.pone.0048463