Liquid Chromatography-Tandem Mass Spectrometry for Analysis of Intestinal Permeability of Loperamide in Physiological Buffer

Analysis of in vitro samples with high salt concentrations represents a major challenge for fast and specific quantification with liquid chromatography-tandem mass spectrometry (LC-MS/MS). To investigate the intestinal permeability of opioids in vitro employing the Ussing chamber technique, we devel...

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Detalles Bibliográficos
Autores principales: Rubelt, Miriam S., Amasheh, Salah, Grobosch, Thomas, Stein, Christoph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493557/
https://www.ncbi.nlm.nih.gov/pubmed/23144895
http://dx.doi.org/10.1371/journal.pone.0048502

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