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DNA-Interactive Properties of Crotamine, a Cell-Penetrating Polypeptide and a Potential Drug Carrier

Crotamine, a 42-residue polypeptide derived from the venom of the South American rattlesnake Crotalus durissus terrificus, has been shown to be a cell-penetrating protein that targets chromosomes, carries plasmid DNA into cells, and shows specificity for actively proliferating cells. Given this pote...

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Detalles Bibliográficos
Autores principales: Chen, Pei-Chun, Hayashi, Mirian A. F., Oliveira, Eduardo Brandt, Karpel, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493588/
https://www.ncbi.nlm.nih.gov/pubmed/23145017
http://dx.doi.org/10.1371/journal.pone.0048913

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