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DNA-Interactive Properties of Crotamine, a Cell-Penetrating Polypeptide and a Potential Drug Carrier
Crotamine, a 42-residue polypeptide derived from the venom of the South American rattlesnake Crotalus durissus terrificus, has been shown to be a cell-penetrating protein that targets chromosomes, carries plasmid DNA into cells, and shows specificity for actively proliferating cells. Given this pote...
Autores principales: | Chen, Pei-Chun, Hayashi, Mirian A. F., Oliveira, Eduardo Brandt, Karpel, Richard L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493588/ https://www.ncbi.nlm.nih.gov/pubmed/23145017 http://dx.doi.org/10.1371/journal.pone.0048913 |
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