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The Hepatitis B Virus X Protein Inhibits Thymine DNA Glycosylase Initiated Base Excision Repair

The hepatitis B virus (HBV) genome encodes the X protein (HBx), a ubiquitous transactivator that is required for HBV replication. Expression of the HBx protein has been associated with the development of HBV infection-related hepatocellular carcinoma (HCC). Previously, we generated a 3D structure of...

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Detalles Bibliográficos
Autores principales: van de Klundert, Maarten A. A., van Hemert, Formijn J., Zaaijer, Hans L., Kootstra, Neeltje A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493593/
https://www.ncbi.nlm.nih.gov/pubmed/23145031
http://dx.doi.org/10.1371/journal.pone.0048940