Otx2 Is Involved in the Regional Specification of the Developing Retinal Pigment Epithelium by Preventing the Expression of Sox2 and Fgf8, Factors That Induce Neural Retina Differentiation

The retinal pigment epithelium (RPE) shares its developmental origin with the neural retina (NR). When RPE development is disrupted, cells in the presumptive RPE region abnormally differentiate into NR-like cells. Therefore, the prevention of NR differentiation in the presumptive RPE area seems to b...

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Detalles Bibliográficos
Autores principales: Nishihara, Daisuke, Yajima, Ichiro, Tabata, Hiromasa, Nakai, Masato, Tsukiji, Nagaharu, Katahira, Tatsuya, Takeda, Kazuhisa, Shibahara, Shigeki, Nakamura, Harukazu, Yamamoto, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493611/
https://www.ncbi.nlm.nih.gov/pubmed/23145006
http://dx.doi.org/10.1371/journal.pone.0048879

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