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The simultaneous ex vivo detection of low-frequency antigen-specific CD4+ and CD8+ T-cell responses using overlapping peptide pools

The ability to measure antigen-specific T cells at the single-cell level by intracellular cytokine staining (ICS) is a promising immunomonitoring tool and is extensively applied in the evaluation of immunotherapy of cancer. The protocols used to detect antigen-specific CD8+ T-cell responses generall...

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Detalles Bibliográficos
Autores principales:	Singh, Satwinder Kaur, Meyering, Maaike, Ramwadhdoebe, Tamara H., Stynenbosch, Linda F. M., Redeker, Anke, Kuppen, Peter J. K., Melief, Cornelis J. M., Welters, Marij J. P., van der Burg, Sjoerd H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer-Verlag 2012
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493661/ https://www.ncbi.nlm.nih.gov/pubmed/22491788 http://dx.doi.org/10.1007/s00262-012-1251-3

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