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Detecting KRAS mutations in peripheral blood of colorectal cancer patients by peptide nucleic acid clamp PCR

We investigated the effectiveness of peptide nucleic acid (PNA) clamp PCR for detecting KRAS mutations in peripheral blood samples of colorectal cancer (CRC) patients. We compared KRAS point mutations between tumour tissue and blood samples. Forty-two patients were included in this study. We observe...

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Detalles Bibliográficos
Autores principales: MIYANO, SHOZO, HANAZAWA, KISABURO, KITABATAKE, TOSHIAKI, FUJISAWA, MINORU, KOJIMA, KUNIAKI
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493693/
https://www.ncbi.nlm.nih.gov/pubmed/23226727
http://dx.doi.org/10.3892/etm.2012.694