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Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study

BACKGROUND: Emotional distress is common in cancer patients. This study aimed to describe, in the year after a cancer diagnosis: the incidence of anxiety, depression and excessive alcohol use; the pattern of these diagnoses and treatment over time; and the nature and duration of the prescribed treat...

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Autores principales: Desplenter, F, Bond, C, Watson, M, Burton, C, Murchie, P, Lee, A J, Lefevre, K, Simoens, S, Laekeman, G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493753/
https://www.ncbi.nlm.nih.gov/pubmed/23059746
http://dx.doi.org/10.1038/bjc.2012.364
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author Desplenter, F
Bond, C
Watson, M
Burton, C
Murchie, P
Lee, A J
Lefevre, K
Simoens, S
Laekeman, G
author_facet Desplenter, F
Bond, C
Watson, M
Burton, C
Murchie, P
Lee, A J
Lefevre, K
Simoens, S
Laekeman, G
author_sort Desplenter, F
collection PubMed
description BACKGROUND: Emotional distress is common in cancer patients. This study aimed to describe, in the year after a cancer diagnosis: the incidence of anxiety, depression and excessive alcohol use; the pattern of these diagnoses and treatment over time; and the nature and duration of the prescribed treatment. METHODS: A matched case–control study was conducted using routinely collected primary care data from 173 Scottish general practices. A presumptive diagnosis of emotional distress (anxiety, depression and/or excessive alcohol use) was based on prescription data or diagnostic code. Prescriptions for psychotropic drugs were described in terms of drug class, volume and treatment duration. RESULTS: In total, 7298 cancer cases and 14 596 matched-controls were identified. Overall, 1135 (15.6%) cases and 201 (1.4%) controls met criteria for emotional distress (odds ratio 13.7, 95% confidence interval 11.6–16.1). Psychotropic drugs were prescribed in the 6 months following initial cancer diagnosis for 1066 (14.6%) cases and 161 (1.1%) controls. The volume and duration of anxiolytic and antipsychotic prescribing was significantly different between cases and controls. CONCLUSION: This study quantified the higher incidence of new emotional distress in cancer patients in the first year post diagnosis. Clinicians should be aware of the possibility of emotional distress at any time in the year after cancer diagnosis.
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spelling pubmed-34937532013-10-23 Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study Desplenter, F Bond, C Watson, M Burton, C Murchie, P Lee, A J Lefevre, K Simoens, S Laekeman, G Br J Cancer Epidemiology BACKGROUND: Emotional distress is common in cancer patients. This study aimed to describe, in the year after a cancer diagnosis: the incidence of anxiety, depression and excessive alcohol use; the pattern of these diagnoses and treatment over time; and the nature and duration of the prescribed treatment. METHODS: A matched case–control study was conducted using routinely collected primary care data from 173 Scottish general practices. A presumptive diagnosis of emotional distress (anxiety, depression and/or excessive alcohol use) was based on prescription data or diagnostic code. Prescriptions for psychotropic drugs were described in terms of drug class, volume and treatment duration. RESULTS: In total, 7298 cancer cases and 14 596 matched-controls were identified. Overall, 1135 (15.6%) cases and 201 (1.4%) controls met criteria for emotional distress (odds ratio 13.7, 95% confidence interval 11.6–16.1). Psychotropic drugs were prescribed in the 6 months following initial cancer diagnosis for 1066 (14.6%) cases and 161 (1.1%) controls. The volume and duration of anxiolytic and antipsychotic prescribing was significantly different between cases and controls. CONCLUSION: This study quantified the higher incidence of new emotional distress in cancer patients in the first year post diagnosis. Clinicians should be aware of the possibility of emotional distress at any time in the year after cancer diagnosis. Nature Publishing Group 2012-10-23 2012-10-11 /pmc/articles/PMC3493753/ /pubmed/23059746 http://dx.doi.org/10.1038/bjc.2012.364 Text en Copyright © 2012 Cancer Research UK https://creativecommons.org/licenses/by-nc-sa/3.0/From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/
spellingShingle Epidemiology
Desplenter, F
Bond, C
Watson, M
Burton, C
Murchie, P
Lee, A J
Lefevre, K
Simoens, S
Laekeman, G
Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
title Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
title_full Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
title_fullStr Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
title_full_unstemmed Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
title_short Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
title_sort incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case–control study
topic Epidemiology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493753/
https://www.ncbi.nlm.nih.gov/pubmed/23059746
http://dx.doi.org/10.1038/bjc.2012.364
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