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Macrophage migration inhibitory factor produced by the tumour stroma but not by tumour cells regulates angiogenesis in the B16-F10 melanoma model

BACKGROUND: Macrophage migration inhibitory factor (MIF) has been proposed as a link between inflammation and tumorigenesis. Despite its potentially broad influence in tumour biology and prevalent expression, the value of MIF as a therapeutic target in cancer remains unclear. We sought to validate M...

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Detalles Bibliográficos
Autores principales: Girard, E, Strathdee, C, Trueblood, E, Quéva, C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493755/
https://www.ncbi.nlm.nih.gov/pubmed/22955855
http://dx.doi.org/10.1038/bjc.2012.392