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Response in bone turnover markers during therapy predicts overall survival in patients with metastatic prostate cancer: analysis of three clinical trials

BACKGROUND: The bone-forming metastases of prostate cancer result from complex stromal–epithelial interactions within the tumour microenvironment. Autocrine–paracrine signalling pathways between prostate cancer epithelial cells, osteoblasts, and osteoclasts stimulate aberrant bone remodelling, and t...

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Detalles Bibliográficos
Autores principales: Som, A, Tu, S-M, Liu, J, Wang, X, Qiao, W, Logothetis, C, Corn, P G
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493771/
https://www.ncbi.nlm.nih.gov/pubmed/23033003
http://dx.doi.org/10.1038/bjc.2012.436

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