Breast cancer and ductal carcinoma in situ among women with prior squamous or glandular precancer in the cervix: a register-based study

BACKGROUND: Human papillomavirus and hormonal contraceptives may be risk factors for cervical precancer and malignant breast tumours. METHODS: Standardised incidence ratios (SIRs) of malignant breast tumours during 1970–2008 were estimated separately for women with prior squamous and glandular cervi...

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Detalles Bibliográficos
Autores principales: Hansen, B T, Nygård, M, Falk, R S, Hofvind, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493773/
https://www.ncbi.nlm.nih.gov/pubmed/23011481
http://dx.doi.org/10.1038/bjc.2012.438
Descripción
Sumario:BACKGROUND: Human papillomavirus and hormonal contraceptives may be risk factors for cervical precancer and malignant breast tumours. METHODS: Standardised incidence ratios (SIRs) of malignant breast tumours during 1970–2008 were estimated separately for women with prior squamous and glandular cervical precancer. RESULTS: Women with squamous precancer and women with glandular precancer in the cervix had a significantly higher risk of malignant breast tumours than the general female population (SIR, 95% confidence interval: 1.10, 1.05–1.14 and 1.52, 1.11–2.08, respectively). INTERPRETATION: Shared risk factors or screening attendance may explain the excess risk of malignant breast tumours among women with a history of cervical precancer.

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