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Elevated expression of artemis in human fibroblast cells is associated with cellular radiosensitivity and increased apoptosis

BACKGROUND: The objective of this study was to determine the molecular mechanisms responsible for cellular radiosensitivity in two human fibroblast cell lines 84BR and 175BR derived from two cancer patients. METHODS: Clonogenic assays were performed following exposure to increasing doses of gamma ra...

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Detalles Bibliográficos
Autores principales:	Ulus-Senguloglu, G, Arlett, C F, Plowman, P N, Parnell, J, Patel, N, Bourton, E C, Parris, C N
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493778/ https://www.ncbi.nlm.nih.gov/pubmed/23093295 http://dx.doi.org/10.1038/bjc.2012.443

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