Promoter and histone methylation and p16(INK4A) gene expression in colon cancer

The inactivation of the cyclin-dependent kinase inhibitor p16(INK4A) gene by hypermethylation is observed in numerous types of cancer. New findings indicate that DNA and histone methylation act in concert in gene silencing. In this study, we investigated the methylation status of the p16(INK4A) gene...

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Detalles Bibliográficos
Autores principales: YORUKER, EBRU ESIN, MERT, UFUK, BUGRA, DURSUN, YAMANER, SUMER, DALAY, NEJAT
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493785/
https://www.ncbi.nlm.nih.gov/pubmed/23226740
http://dx.doi.org/10.3892/etm.2012.683

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493785/
https://www.ncbi.nlm.nih.gov/pubmed/23226740
http://dx.doi.org/10.3892/etm.2012.683

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