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The FOXM1-PLK1 axis is commonly upregulated in oesophageal adenocarcinoma

BACKGROUND: The transcription factor FOXM1 is an important regulator of the cell cycle through controlling periodic gene expression during the G2 and M phases. One key target for FOXM1 is the gene encoding the protein kinase PLK1 and PLK1 itself acts in a positive feedback loop to phosphorylate and...

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Detalles Bibliográficos
Autores principales:	Dibb, M, Han, N, Choudhury, J, Hayes, S, Valentine, H, West, C, Ang, Y S, Sharrocks, A D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2012
Materias:	Genetics & Genomics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493860/ https://www.ncbi.nlm.nih.gov/pubmed/23037713 http://dx.doi.org/10.1038/bjc.2012.424

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