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Immunomodulatory glycan LNFPIII alleviates hepatosteatosis and insulin resistance through direct and indirect control of metabolic pathways
Parasitic worms express host-like glycans to attenuate the immune response of human hosts. The therapeutic potential of this immunomodulatory mechanism in controlling metabolic dysfunction associated with chronic inflammation remains unexplored. We demonstrate here that administration of Lacto-N-fuc...
Autores principales: | Bhargava, Prerna, Li, Changlin, Stanya, Kristopher J., Jacobi, David, Dai, Lingling, Liu, Sihao, Gangl, Matthew R., Harn, Donald A., Lee, Chih-Hao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3493877/ https://www.ncbi.nlm.nih.gov/pubmed/23104131 http://dx.doi.org/10.1038/nm.2962 |
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