Loss of Maternal Annexin A5 Increases the Likelihood of Placental Platelet Thrombosis and Foetal Loss

Antiphospholipid syndrome is associated with an increased risk of thrombosis and pregnancy loss. Annexin A5 (Anxa5) is a candidate autoantigen. It is not known, however, whether endogenous Anxa5 prevents foetal loss during normal pregnancy. We found significant reductions in litter size and foetal w...

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Detalles Bibliográficos
Autores principales: Ueki, Hiroshi, Mizushina, Tomona, Laoharatchatathanin, Titaree, Terashima, Ryota, Nishimura, Yasuhiro, Rieanrakwong, Duangjai, Yonezawa, Tomohiro, Kurusu, Shiro, Hasegawa, Yoshihisa, Brachvogel, Bent, Pöschl, Ernst, Kawaminami, Mitsumori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494014/
https://www.ncbi.nlm.nih.gov/pubmed/23145320
http://dx.doi.org/10.1038/srep00827

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