Igf2 pathway dependency of the Trp53 developmental and tumour phenotypes

Insulin-like growth factor 2 (IGF2) and the transformation related protein 53 (Trp53) are potent regulators of cell growth and metabolism in development and cancer. In vitro evidence suggests several mechanistic pathway interactions. Here, we tested whether loss of function of p53 leads to IGF2 liga...

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Detalles Bibliográficos
Autores principales: Haley, Victoria L, Barnes, David J, Sandovici, Ionel, Constancia, Miguel, Graham, Christopher F, Pezzella, Francesco, Bühnemann, Claudia, Carter, Emma J, Hassan, A Bassim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: WILEY-VCH Verlag 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494071/
https://www.ncbi.nlm.nih.gov/pubmed/22674894
http://dx.doi.org/10.1002/emmm.201101105

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494071/
https://www.ncbi.nlm.nih.gov/pubmed/22674894
http://dx.doi.org/10.1002/emmm.201101105

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