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GSTP1 methylation and polymorphism increase the risk of breast cancer and the effects of diet and lifestyle in breast cancer patients

Glutathione S-transferases (GSTs) are an important group of isoenzymes that play an essential role in the detoxification of carcinogens. Polymorphism at exon 5 of the GST π family decreases the catalytic activity and affects the detoxification ability of the enzyme, GSTP1. GSTP1 promoter hypermethyl...

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Detalles Bibliográficos
Autores principales: SAXENA, ANUBHA, DHILLON, VARINDERPAL S., SHAHID, MOHAMMAD, KHALIL, HESHAM SALEH, RANI, MADHU, PRASAD DAS, TRINATH, HEDAU, SURESH, HUSSAIN, ARIF, NAQVI, RAZA ALI, DEO, S.V.S., SHUKLA, N.K., DAS, B.C., HUSAIN, SYED AKHTAR
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494109/
https://www.ncbi.nlm.nih.gov/pubmed/23226781
http://dx.doi.org/10.3892/etm.2012.710