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Primary sterile necrotic cells fail to cross-prime CD8(+) T cells
Necrotic cells are known to activate the innate immune system and trigger inflammation by releasing damage associated molecular patterns (DAMPs). However, how necrotic cells influence the induction of antigen-specific CD8(+) T cell-mediated adaptive immune responses under sterile conditions, in the...
Autores principales: | Gamrekelashvili, Jaba, Ormandy, Lars A., Heimesaat, Markus M., Kirschning, Carsten J., Manns, Michael P., Korangy, Firouzeh, Greten, Tim F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494616/ https://www.ncbi.nlm.nih.gov/pubmed/23170250 http://dx.doi.org/10.4161/onci.21098 |
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