Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients

BCR-ABL(+) K562 cells hold clinical promise as a component of cancer vaccines, either as bystander cells genetically modified to express immunostimulatory molecules, or as a source of leukemia antigens. To develop a method for detecting T-cell reactivity against K562 cell-derived antigens in patient...

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Detalles Bibliográficos
Autores principales: Brusic, Ana, Hainz, Ursula, Wadleigh, Martha, Neuberg, Donna, Su, Mei, Canning, Christine M., DeAngelo, Daniel J., Stone, Richard M., Lee, Jeng-Shin, Mulligan, Richard C., Ritz, Jerome, Dranoff, Glenn, Sasada, Tetsuro, Wu, Catherine J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494623/
https://www.ncbi.nlm.nih.gov/pubmed/23170257
http://dx.doi.org/10.4161/onci.20954

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