Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors

Infiltration of plasma cells is associated with better prognosis in breast, lung and colon cancer. Immunoglobulin κ chain (IGKC) is now available as a single, robust immune marker predicting metastasis-free survival and response to chemotherapy. This will facilitate a deeper understanding of the rol...

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Autores principales: Schmidt, Marcus, Micke, Patrick, Gehrmann, Mathias, Hengstler, Jan G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Point of View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494628/
https://www.ncbi.nlm.nih.gov/pubmed/23170262
http://dx.doi.org/10.4161/onci.21653
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author Schmidt, Marcus
Micke, Patrick
Gehrmann, Mathias
Hengstler, Jan G.
author_facet Schmidt, Marcus
Micke, Patrick
Gehrmann, Mathias
Hengstler, Jan G.
author_sort Schmidt, Marcus
collection PubMed
description Infiltration of plasma cells is associated with better prognosis in breast, lung and colon cancer. Immunoglobulin κ chain (IGKC) is now available as a single, robust immune marker predicting metastasis-free survival and response to chemotherapy. This will facilitate a deeper understanding of the role of the humoral immune system in cancer development.
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spelling pubmed-34946282012-11-20 Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors Schmidt, Marcus Micke, Patrick Gehrmann, Mathias Hengstler, Jan G. Oncoimmunology Point of View Infiltration of plasma cells is associated with better prognosis in breast, lung and colon cancer. Immunoglobulin κ chain (IGKC) is now available as a single, robust immune marker predicting metastasis-free survival and response to chemotherapy. This will facilitate a deeper understanding of the role of the humoral immune system in cancer development. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494628/ /pubmed/23170262 http://dx.doi.org/10.4161/onci.21653 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Point of View
Schmidt, Marcus
Micke, Patrick
Gehrmann, Mathias
Hengstler, Jan G.
Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
title Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
title_full Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
title_fullStr Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
title_full_unstemmed Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
title_short Immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
title_sort immunoglobulin kappa chain as an immunologic biomarker of prognosis and chemotherapy response in solid tumors
topic Point of View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494628/
https://www.ncbi.nlm.nih.gov/pubmed/23170262
http://dx.doi.org/10.4161/onci.21653
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