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Friend or foe: A novel role of β-defensins in tumor development
For many years, β-defensins were best known for their antimicrobial activity. However, β-defensins also exert immunomodulatory functions, such as the chemotactic recruitment of immune cells via chemokine receptors. We demonstrated that mouse β-defensin 14 recruits CCR6(+) B cells into fibrosarcomas,...
Autores principales: | Röhrl, Johann, Geissler, Edward K., Hehlgans, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494629/ https://www.ncbi.nlm.nih.gov/pubmed/23170263 http://dx.doi.org/10.4161/onci.20825 |
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