Hunting for clues: Regulatory T cells and colorectal cancer

Colorectal cancer is a common disease which appears to be influenced by anti-tumor immune responses. Here we discuss our recent study(1) which tracked anti-tumor CD4(+) T cell responses before and after surgical resection, highlighting the importance of regulatory T cells (T(regs)) in controlling th...

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Detalles Bibliográficos
Autores principales: Gallimore, Awen, Godkin, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494631/
https://www.ncbi.nlm.nih.gov/pubmed/23170265
http://dx.doi.org/10.4161/onci.20499
Descripción
Sumario:Colorectal cancer is a common disease which appears to be influenced by anti-tumor immune responses. Here we discuss our recent study(1) which tracked anti-tumor CD4(+) T cell responses before and after surgical resection, highlighting the importance of regulatory T cells (T(regs)) in controlling these responses, and the influence of the tumor on these specific T‑cell populations.

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