Personalizing immunotherapy: Balancing predictability and precision

Despite great expectations and research efforts, anticancer immunotherapy has not yet become a definitive cure. Perhaps, this is because past reductionist approaches were too simplistic for the patient-specific complex system of co-evolving tumor cells and host immunity. Recent efforts based on a sy...

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Detalles Bibliográficos
Autores principales: Agur, Zvia, Vuk-Pavlović, Stanimir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494634/
https://www.ncbi.nlm.nih.gov/pubmed/23170268
http://dx.doi.org/10.4161/onci.20955
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author Agur, Zvia
Vuk-Pavlović, Stanimir
author_facet Agur, Zvia
Vuk-Pavlović, Stanimir
author_sort Agur, Zvia
collection PubMed
description Despite great expectations and research efforts, anticancer immunotherapy has not yet become a definitive cure. Perhaps, this is because past reductionist approaches were too simplistic for the patient-specific complex system of co-evolving tumor cells and host immunity. Recent efforts based on a systems-based approach promise improved clinical outcomes engendered by a dynamic modification of personalized therapeutic regimens.
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spelling pubmed-34946342012-11-20 Personalizing immunotherapy: Balancing predictability and precision Agur, Zvia Vuk-Pavlović, Stanimir Oncoimmunology Author's View Despite great expectations and research efforts, anticancer immunotherapy has not yet become a definitive cure. Perhaps, this is because past reductionist approaches were too simplistic for the patient-specific complex system of co-evolving tumor cells and host immunity. Recent efforts based on a systems-based approach promise improved clinical outcomes engendered by a dynamic modification of personalized therapeutic regimens. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494634/ /pubmed/23170268 http://dx.doi.org/10.4161/onci.20955 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Agur, Zvia
Vuk-Pavlović, Stanimir
Personalizing immunotherapy: Balancing predictability and precision
title Personalizing immunotherapy: Balancing predictability and precision
title_full Personalizing immunotherapy: Balancing predictability and precision
title_fullStr Personalizing immunotherapy: Balancing predictability and precision
title_full_unstemmed Personalizing immunotherapy: Balancing predictability and precision
title_short Personalizing immunotherapy: Balancing predictability and precision
title_sort personalizing immunotherapy: balancing predictability and precision
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494634/
https://www.ncbi.nlm.nih.gov/pubmed/23170268
http://dx.doi.org/10.4161/onci.20955
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