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RhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment
Low expression of RhoGDI2 is associated with poor outcome in cancer patients. In animal models, RhoGDI2 suppresses lung metastasis by reducing the expression of the proteoglycan versican, whose levels portend poor patient prognosis. Versican promotes metastasis through enhanced tumor migration and c...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Landes Bioscience
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494636/ https://www.ncbi.nlm.nih.gov/pubmed/23170270 http://dx.doi.org/10.4161/onci.20594 |