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RhoGDI2 suppresses bladder cancer metastasis via reduction of inflammation in the tumor microenvironment

Low expression of RhoGDI2 is associated with poor outcome in cancer patients. In animal models, RhoGDI2 suppresses lung metastasis by reducing the expression of the proteoglycan versican, whose levels portend poor patient prognosis. Versican promotes metastasis through enhanced tumor migration and c...

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Detalles Bibliográficos
Autores principales: Said, Neveen, Theodorescu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494636/
https://www.ncbi.nlm.nih.gov/pubmed/23170270
http://dx.doi.org/10.4161/onci.20594

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