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Tumor-infiltrating B cells: The ignored players in tumor immunology
B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-in...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494640/ https://www.ncbi.nlm.nih.gov/pubmed/23170274 http://dx.doi.org/10.4161/onci.20641 |
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author | Linnebacher, Michael Maletzki, Claudia |
author_facet | Linnebacher, Michael Maletzki, Claudia |
author_sort | Linnebacher, Michael |
collection | PubMed |
description | B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-infiltrating B lymphocyte cloning may prove helpful in unraveling the actual relevance of these cells for tumor development and response to therapy. |
format | Online Article Text |
id | pubmed-3494640 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Landes Bioscience |
record_format | MEDLINE/PubMed |
spelling | pubmed-34946402012-11-20 Tumor-infiltrating B cells: The ignored players in tumor immunology Linnebacher, Michael Maletzki, Claudia Oncoimmunology Author's View B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-infiltrating B lymphocyte cloning may prove helpful in unraveling the actual relevance of these cells for tumor development and response to therapy. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494640/ /pubmed/23170274 http://dx.doi.org/10.4161/onci.20641 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited. |
spellingShingle | Author's View Linnebacher, Michael Maletzki, Claudia Tumor-infiltrating B cells: The ignored players in tumor immunology |
title | Tumor-infiltrating B cells: The ignored players in tumor immunology |
title_full | Tumor-infiltrating B cells: The ignored players in tumor immunology |
title_fullStr | Tumor-infiltrating B cells: The ignored players in tumor immunology |
title_full_unstemmed | Tumor-infiltrating B cells: The ignored players in tumor immunology |
title_short | Tumor-infiltrating B cells: The ignored players in tumor immunology |
title_sort | tumor-infiltrating b cells: the ignored players in tumor immunology |
topic | Author's View |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494640/ https://www.ncbi.nlm.nih.gov/pubmed/23170274 http://dx.doi.org/10.4161/onci.20641 |
work_keys_str_mv | AT linnebachermichael tumorinfiltratingbcellstheignoredplayersintumorimmunology AT maletzkiclaudia tumorinfiltratingbcellstheignoredplayersintumorimmunology |