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Tumor-infiltrating B cells: The ignored players in tumor immunology

B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-in...

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Detalles Bibliográficos
Autores principales: Linnebacher, Michael, Maletzki, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494640/
https://www.ncbi.nlm.nih.gov/pubmed/23170274
http://dx.doi.org/10.4161/onci.20641
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author Linnebacher, Michael
Maletzki, Claudia
author_facet Linnebacher, Michael
Maletzki, Claudia
author_sort Linnebacher, Michael
collection PubMed
description B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-infiltrating B lymphocyte cloning may prove helpful in unraveling the actual relevance of these cells for tumor development and response to therapy.
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spelling pubmed-34946402012-11-20 Tumor-infiltrating B cells: The ignored players in tumor immunology Linnebacher, Michael Maletzki, Claudia Oncoimmunology Author's View B cells infiltrating into solid tumors are poorly investigated despite their described positive prognostic value. Whether this antitumor potential comes from either the antigen presentation or the antibody production capacity of B cells, or both, is unknown. Our recently published method on tumor-infiltrating B lymphocyte cloning may prove helpful in unraveling the actual relevance of these cells for tumor development and response to therapy. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494640/ /pubmed/23170274 http://dx.doi.org/10.4161/onci.20641 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Linnebacher, Michael
Maletzki, Claudia
Tumor-infiltrating B cells: The ignored players in tumor immunology
title Tumor-infiltrating B cells: The ignored players in tumor immunology
title_full Tumor-infiltrating B cells: The ignored players in tumor immunology
title_fullStr Tumor-infiltrating B cells: The ignored players in tumor immunology
title_full_unstemmed Tumor-infiltrating B cells: The ignored players in tumor immunology
title_short Tumor-infiltrating B cells: The ignored players in tumor immunology
title_sort tumor-infiltrating b cells: the ignored players in tumor immunology
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494640/
https://www.ncbi.nlm.nih.gov/pubmed/23170274
http://dx.doi.org/10.4161/onci.20641
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