Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells

Oncogenes have been traditionally viewed as molecular drivers for tumor growth and survival. Recent evidence indicates that oncogenes may facilitate the escape of malignant cells from immune recognition and elimination. In this article, we discuss the implications of the overexpression of epidermal...

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Autores principales: Kiessling, Rolf, Okita, Riki, Mougiakakos, Dimitrios, Mao, Yumeng, Sarhan, Dhifaf, Wennerberg, Erik, Seliger, Barbara, Lundqvist, Andreas, Mimura, Kousaku, Kono, Koji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494645/
https://www.ncbi.nlm.nih.gov/pubmed/23170279
http://dx.doi.org/10.4161/onci.20685
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author Kiessling, Rolf
Okita, Riki
Mougiakakos, Dimitrios
Mao, Yumeng
Sarhan, Dhifaf
Wennerberg, Erik
Seliger, Barbara
Lundqvist, Andreas
Mimura, Kousaku
Kono, Koji
author_facet Kiessling, Rolf
Okita, Riki
Mougiakakos, Dimitrios
Mao, Yumeng
Sarhan, Dhifaf
Wennerberg, Erik
Seliger, Barbara
Lundqvist, Andreas
Mimura, Kousaku
Kono, Koji
author_sort Kiessling, Rolf
collection PubMed
description Oncogenes have been traditionally viewed as molecular drivers for tumor growth and survival. Recent evidence indicates that oncogenes may facilitate the escape of malignant cells from immune recognition and elimination. In this article, we discuss the implications of the overexpression of epidermal growth factor receptor (EGFR) family members on immune escape of tumors and immunotherapy.
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spelling pubmed-34946452012-11-20 Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells Kiessling, Rolf Okita, Riki Mougiakakos, Dimitrios Mao, Yumeng Sarhan, Dhifaf Wennerberg, Erik Seliger, Barbara Lundqvist, Andreas Mimura, Kousaku Kono, Koji Oncoimmunology Author's View Oncogenes have been traditionally viewed as molecular drivers for tumor growth and survival. Recent evidence indicates that oncogenes may facilitate the escape of malignant cells from immune recognition and elimination. In this article, we discuss the implications of the overexpression of epidermal growth factor receptor (EGFR) family members on immune escape of tumors and immunotherapy. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494645/ /pubmed/23170279 http://dx.doi.org/10.4161/onci.20685 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Kiessling, Rolf
Okita, Riki
Mougiakakos, Dimitrios
Mao, Yumeng
Sarhan, Dhifaf
Wennerberg, Erik
Seliger, Barbara
Lundqvist, Andreas
Mimura, Kousaku
Kono, Koji
Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells
title Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells
title_full Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells
title_fullStr Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells
title_full_unstemmed Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells
title_short Opposing consequences of signaling through EGF family members: Escape from CTLs could be a bait for NK cells
title_sort opposing consequences of signaling through egf family members: escape from ctls could be a bait for nk cells
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494645/
https://www.ncbi.nlm.nih.gov/pubmed/23170279
http://dx.doi.org/10.4161/onci.20685
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