CD4 responses against IDO

Natural indoleamine-2,3-dioxygenase (IDO)-reactive CD4(+) T cells have been shown to release interferonγ (IFNγ), tumor necrosis factor α (TNFα), as well as interleukin 17 (IL-17). In some individuals, these cells also demonstrated the ability to suppress IL-10 production. IDO-specific CD4(+) helper...

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Detalles Bibliográficos
Autor principal: Andersen, Mads Hald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494649/
https://www.ncbi.nlm.nih.gov/pubmed/23170283
http://dx.doi.org/10.4161/onci.20780
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author Andersen, Mads Hald
author_facet Andersen, Mads Hald
author_sort Andersen, Mads Hald
collection PubMed
description Natural indoleamine-2,3-dioxygenase (IDO)-reactive CD4(+) T cells have been shown to release interferonγ (IFNγ), tumor necrosis factor α (TNFα), as well as interleukin 17 (IL-17). In some individuals, these cells also demonstrated the ability to suppress IL-10 production. IDO-specific CD4(+) helper T cells among peripheral blood lymphocytes may participate in immunoregulatory networks by delaying the immune suppressive actions of IDO. However, IDO-specific CD4(+) T cells may also have a regulatory phenotype, de facto exerting immunosuppressive functions.
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spelling pubmed-34946492012-11-20 CD4 responses against IDO Andersen, Mads Hald Oncoimmunology Author's View Natural indoleamine-2,3-dioxygenase (IDO)-reactive CD4(+) T cells have been shown to release interferonγ (IFNγ), tumor necrosis factor α (TNFα), as well as interleukin 17 (IL-17). In some individuals, these cells also demonstrated the ability to suppress IL-10 production. IDO-specific CD4(+) helper T cells among peripheral blood lymphocytes may participate in immunoregulatory networks by delaying the immune suppressive actions of IDO. However, IDO-specific CD4(+) T cells may also have a regulatory phenotype, de facto exerting immunosuppressive functions. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494649/ /pubmed/23170283 http://dx.doi.org/10.4161/onci.20780 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Andersen, Mads Hald
CD4 responses against IDO
title CD4 responses against IDO
title_full CD4 responses against IDO
title_fullStr CD4 responses against IDO
title_full_unstemmed CD4 responses against IDO
title_short CD4 responses against IDO
title_sort cd4 responses against ido
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494649/
https://www.ncbi.nlm.nih.gov/pubmed/23170283
http://dx.doi.org/10.4161/onci.20780
work_keys_str_mv AT andersenmadshald cd4responsesagainstido

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