Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15

Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for an...

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Detalles Bibliográficos
Autor principal: Müller, Dafne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494650/
https://www.ncbi.nlm.nih.gov/pubmed/23170284
http://dx.doi.org/10.4161/onci.20824
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author Müller, Dafne
author_facet Müller, Dafne
author_sort Müller, Dafne
collection PubMed
description Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for anticancer immunotherapy.
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spelling pubmed-34946502012-11-20 Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15 Müller, Dafne Oncoimmunology Author's View Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for anticancer immunotherapy. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494650/ /pubmed/23170284 http://dx.doi.org/10.4161/onci.20824 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Müller, Dafne
Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
title Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
title_full Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
title_fullStr Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
title_full_unstemmed Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
title_short Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15
title_sort targeted cancer immunotherapy: mimicking physiological trans-presentation of il-15
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494650/
https://www.ncbi.nlm.nih.gov/pubmed/23170284
http://dx.doi.org/10.4161/onci.20824
work_keys_str_mv AT mullerdafne targetedcancerimmunotherapymimickingphysiologicaltranspresentationofil15

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