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Targeted cancer immunotherapy: Mimicking physiological trans-presentation of IL-15

Under physiological conditions, the trans-presentation of interleukin-15 (IL-15) by the IL-15 receptor α on the cell surface allows to confine and tune the IL-15-mediated immune responses. Therefore, targeting strategies that mimic this situation at the tumor sites appear especially promising for an...

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Detalles Bibliográficos
Autor principal: Müller, Dafne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494650/
https://www.ncbi.nlm.nih.gov/pubmed/23170284
http://dx.doi.org/10.4161/onci.20824

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