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Production of epitope-specific antibodies using peptide-CpG-ODN-liposome complex without carriers and their application as a cancer vaccine in mice
Low efficacy of peptide vaccines limits their potential application. We developed a powerful strategy to produce epitope-specific antibodies using peptides. Immunization with novel formula into mice showed target-specific prophylactic and therapeutic effects against tumors. Our strategy will be usef...
Autores principales: | Lee, YoungHee, Kwon, Hyung-Joo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494651/ https://www.ncbi.nlm.nih.gov/pubmed/23170285 http://dx.doi.org/10.4161/onci.20404 |
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