Opposing effects of androgen ablation on immune function in prostate cancer

Although it is recognized that immune function is modulated by androgen ablation therapy for prostate cancer, the long-term consequences are not completely understood. We recently showed that both effector and inhibitory immune mechanisms are amplified by androgen ablation, providing one explanation...

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Detalles Bibliográficos
Autores principales: Tang, Shuai, Dubey, Purnima
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494653/
https://www.ncbi.nlm.nih.gov/pubmed/23170287
http://dx.doi.org/10.4161/onci.20448
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author Tang, Shuai
Dubey, Purnima
author_facet Tang, Shuai
Dubey, Purnima
author_sort Tang, Shuai
collection PubMed
description Although it is recognized that immune function is modulated by androgen ablation therapy for prostate cancer, the long-term consequences are not completely understood. We recently showed that both effector and inhibitory immune mechanisms are amplified by androgen ablation, providing one explanation for only transient increases in immune function after castration.
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spelling pubmed-34946532012-11-20 Opposing effects of androgen ablation on immune function in prostate cancer Tang, Shuai Dubey, Purnima Oncoimmunology Author's View Although it is recognized that immune function is modulated by androgen ablation therapy for prostate cancer, the long-term consequences are not completely understood. We recently showed that both effector and inhibitory immune mechanisms are amplified by androgen ablation, providing one explanation for only transient increases in immune function after castration. Landes Bioscience 2012-10-01 /pmc/articles/PMC3494653/ /pubmed/23170287 http://dx.doi.org/10.4161/onci.20448 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Tang, Shuai
Dubey, Purnima
Opposing effects of androgen ablation on immune function in prostate cancer
title Opposing effects of androgen ablation on immune function in prostate cancer
title_full Opposing effects of androgen ablation on immune function in prostate cancer
title_fullStr Opposing effects of androgen ablation on immune function in prostate cancer
title_full_unstemmed Opposing effects of androgen ablation on immune function in prostate cancer
title_short Opposing effects of androgen ablation on immune function in prostate cancer
title_sort opposing effects of androgen ablation on immune function in prostate cancer
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494653/
https://www.ncbi.nlm.nih.gov/pubmed/23170287
http://dx.doi.org/10.4161/onci.20448
work_keys_str_mv AT tangshuai opposingeffectsofandrogenablationonimmunefunctioninprostatecancer
AT dubeypurnima opposingeffectsofandrogenablationonimmunefunctioninprostatecancer

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