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Protein Secretion Is Required for Pregnancy-Associated Plasma Protein-A to Promote Lung Cancer Growth In Vivo

Pregnancy-associated plasma protein-A (PAPPA) has been reported to regulate the activity of insulin-like growth factor (IGF) signal pathway through proteolytic degradation of IGF binding proteins (IGFBPs) thereby increasing the local concentration of free IGFs available to receptors. In this study w...

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Detalles Bibliográficos
Autores principales:	Pan, Hong, Hanada, Sayaka, Zhao, Jun, Mao, Li, Ma, Mark Zhi-Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494721/ https://www.ncbi.nlm.nih.gov/pubmed/23152806 http://dx.doi.org/10.1371/journal.pone.0048799

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