Cdc42 promotes transendothelial migration of cancer cells through β1 integrin

Cancer cells interact with endothelial cells during the process of metastatic spreading. Here, we use a small interfering RNA screen targeting Rho GTPases in cancer cells to identify Cdc42 as a critical regulator of cancer cell–endothelial cell interactions and transendothelial migration. We find th...

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Detalles Bibliográficos
Autores principales: Reymond, Nicolas, Im, Jae Hong, Garg, Ritu, Vega, Francisco M., Borda d’Agua, Barbara, Riou, Philippe, Cox, Susan, Valderrama, Ferran, Muschel, Ruth J., Ridley, Anne J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494849/
https://www.ncbi.nlm.nih.gov/pubmed/23148235
http://dx.doi.org/10.1083/jcb.201205169

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494849/
https://www.ncbi.nlm.nih.gov/pubmed/23148235
http://dx.doi.org/10.1083/jcb.201205169

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