Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses

Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell’s autophagic process. Here, we review the interactions between viruses and cells in...

Descripción completa

Detalles Bibliográficos
Autores principales: Tang, Sai-Wen, Ducroux, Aurelie, Jeang, Kuan-Teh, Neuveut, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495035/
https://www.ncbi.nlm.nih.gov/pubmed/23110561
http://dx.doi.org/10.1186/1423-0127-19-92
_version_ 1782249457615634432
author Tang, Sai-Wen
Ducroux, Aurelie
Jeang, Kuan-Teh
Neuveut, Christine
author_facet Tang, Sai-Wen
Ducroux, Aurelie
Jeang, Kuan-Teh
Neuveut, Christine
author_sort Tang, Sai-Wen
collection PubMed
description Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell’s autophagic process. Here, we review the interactions between viruses and cells in regards to cellular autophagy. Using findings from hepatitis B virus and human retroviruses, HIV-1 and HTLV-1, we discuss mechanisms used by viruses to usurp cellular autophagy in ways that benefit viral replication.
format Online
Article
Text
id pubmed-3495035
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-34950352012-11-11 Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses Tang, Sai-Wen Ducroux, Aurelie Jeang, Kuan-Teh Neuveut, Christine J Biomed Sci Review Autophagy is a protein degradative process important for normal cellular metabolism. It is apparently used also by cells to eliminate invading pathogens. Interestingly, many pathogens have learned to subvert the cell’s autophagic process. Here, we review the interactions between viruses and cells in regards to cellular autophagy. Using findings from hepatitis B virus and human retroviruses, HIV-1 and HTLV-1, we discuss mechanisms used by viruses to usurp cellular autophagy in ways that benefit viral replication. BioMed Central 2012-10-30 /pmc/articles/PMC3495035/ /pubmed/23110561 http://dx.doi.org/10.1186/1423-0127-19-92 Text en Copyright ©2012 Tang et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Tang, Sai-Wen
Ducroux, Aurelie
Jeang, Kuan-Teh
Neuveut, Christine
Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
title Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
title_full Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
title_fullStr Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
title_full_unstemmed Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
title_short Impact of cellular autophagy on viruses: Insights from hepatitis B virus and human retroviruses
title_sort impact of cellular autophagy on viruses: insights from hepatitis b virus and human retroviruses
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495035/
https://www.ncbi.nlm.nih.gov/pubmed/23110561
http://dx.doi.org/10.1186/1423-0127-19-92
work_keys_str_mv AT tangsaiwen impactofcellularautophagyonvirusesinsightsfromhepatitisbvirusandhumanretroviruses
AT ducrouxaurelie impactofcellularautophagyonvirusesinsightsfromhepatitisbvirusandhumanretroviruses
AT jeangkuanteh impactofcellularautophagyonvirusesinsightsfromhepatitisbvirusandhumanretroviruses
AT neuveutchristine impactofcellularautophagyonvirusesinsightsfromhepatitisbvirusandhumanretroviruses

Ejemplares similares