PNPLA 3 I148M genetic variant associates with insulin resistance and baseline viral load in HCV genotype 2 but not in genotype 3 infection

BACKGROUND: Hepatic steatosis in HCV patients has been postulated as a risk factor associated with a higher frequency of fibrosis and cirrhosis. A single genetic variant, PNPLA3 I148M, has been widely associated with increased hepatic steatosis. Previous studies of the PNPLA3 I148M sequence variant...

Descripción completa

Detalles Bibliográficos
Autores principales: Rembeck, Karolina, Maglio, Cristina, Lagging, Martin, Christensen, Peer Brehm, Färkkilä, Martti, Langeland, Nina, Buhl, Mads Rauning, Pedersen, Court, Mørch, Kristine, Norkrans, Gunnar, Hellstrand, Kristoffer, Lindh, Magnus, Pirazzi, Carlo, Burza, Maria Antonella, Romeo, Stefano, Westin, Johan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495049/
https://www.ncbi.nlm.nih.gov/pubmed/22978414
http://dx.doi.org/10.1186/1471-2350-13-82

Ejemplares similares

Ejemplares similares