BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice

Current therapy for patients with hereditary absence of cochlear hair cells, who have severe or profound deafness, is restricted to cochlear implantation, a procedure that requires survival of the auditory nerve. Mouse mutations that serve as models for genetic deafness can be utilized for developin...

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Detalles Bibliográficos
Autores principales: Fukui, H., Wong, H. T., Beyer, L. A., Case, B. G., Swiderski, D. L., Di Polo, A., Ryan, A. F., Raphael, Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495341/
https://www.ncbi.nlm.nih.gov/pubmed/23150788
http://dx.doi.org/10.1038/srep00838

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495341/
https://www.ncbi.nlm.nih.gov/pubmed/23150788
http://dx.doi.org/10.1038/srep00838

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