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BDNF gene therapy induces auditory nerve survival and fiber sprouting in deaf Pou4f3 mutant mice
Current therapy for patients with hereditary absence of cochlear hair cells, who have severe or profound deafness, is restricted to cochlear implantation, a procedure that requires survival of the auditory nerve. Mouse mutations that serve as models for genetic deafness can be utilized for developin...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3495341/ https://www.ncbi.nlm.nih.gov/pubmed/23150788 http://dx.doi.org/10.1038/srep00838 |